Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under the trade name ROBAXIN, The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase.
robaxin®/robaxin®- 750 (methocarbamol tablets, USP), a carbamate derivative of guaifenesin, is central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties.
The chemical name of methocarbamol is (2-methoxyphenoxy) 1,2propanediol 1-carbamate and has the empirical formula C11H15NO5. Its molecular weight is 241.24. The structural formula is shown below.
Methocarbamol is a white powder, sparingly soluble in water and chloroform, soluble in alcohol (only with heating) and propylene glycol, and insoluble in benzene and n-hexane.
robaxin® is available as a light orange, round, filmcoated tablet containing 500 mg of methocarbamol, USP for oral administration. The inactive ingredients present are corn starch, FD&C Yellow 6, hydroxypropyl cellulose, hypromellose, magnesium stearate, polysorbate 20, povidone, propylene glycol,
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